The EFG-ring system of pectenotoxin-4 was synthesised via a novel pathway which ultilised a cobalt-mediated oxidative cyclisation to access the trans F-ring, and an osmium-mediated oxidative cyclisation to form the cis E-ring.
Subsequent union of these fragments, under modified Julia-Kocienski olefination conditions, facilitated the synthesis of the EFG-ring system of pectenotoxin-4.
This chapter reports the previous total syntheses of pectenotoxin ...Expand abstract
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