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Thesis

The influence of selected flavonoids on the survival of retinal ganglion cells subjected to different types of oxidative stress

Abstract:

The general aim of the thesis was to deduce whether selected naturally occurring flavonoids (genistein, epicatechin gallate (EC), epigallocatechin gallate (EGCG), baicalin) attenuate various secondary insults that may cause death of ganglion cells in primary open angle glaucoma (POAG).

An ischemic insult to the rat retina significantly causes the inner retina to degenerate indexed by changes of various antigens, proteins and mRNAs located to amacrine and ganglion cells. These change...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
Green Templeton College
Role:
Author

Contributors

Division:
MSD
Department:
Clinical Neurosciences
Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:5e4ea0b8-3558-452a-b106-95f5109d962a
Local pid:
ora:12091
Deposit date:
2015-08-05

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