Journal article
The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy.
- Abstract:
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Pathological alterations in cell functions are frequently accompanied by metabolic reprogramming including modifications in amino acid metabolism. Amino acid detection is thus integral to the diagnosis of many hereditary metabolic diseases. The development of malignant diseases as metabolic disorders comes along with a complex dysregulation of genetic and epigenetic factors affecting metabolic enzymes. Cancer cells might transiently or permanently become auxotrophic for non-essential or semi-...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Accepted manuscript, pdf, 560.1KB, Terms of use)
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(Preview, Accepted manuscript, pdf, 287.6KB, Terms of use)
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(Preview, Accepted manuscript, pdf, 465.0KB, Terms of use)
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- Publisher copy:
- 10.1016/j.jbiotec.2016.12.001
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Funding
Bibliographic Details
- Publisher:
- Elsevier
- Journal:
- Journal of Biotechnology More from this journal
- Volume:
- 244
- Pages:
- 30–54
- Publication date:
- 2016-12-05
- Acceptance date:
- 2016-12-01
- DOI:
- ISSN:
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0168-1656 and 1873-4863
Item Description
- Language:
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English
- Keywords:
- Pubs id:
-
pubs:666039
- UUID:
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uuid:5e49ca9e-1922-4638-8c94-4d5ae8d638aa
- Local pid:
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pubs:666039
- Source identifiers:
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666039
- Deposit date:
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2016-12-21
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2016
- Notes:
- © 2016 Elsevier B.V. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: [10.1016/j.jbiotec.2016.12.001].
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