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Thesis

Cardiac sympathetic neural signalling in hypertension

Abstract:

The work presented in this thesis examines the role of cardiac sympathetic signalling in the development and maintenance of hypertension in the spontaneously hypertensive rat (SHR); and the role the norepinephrine re-uptake transporter (NET) plays in the sympathetic phenotype during hypertension.

Chapter One: reviews (i) cardiac impairment observed in hypertension, (ii) the mechanisms underlying sympathetic neurotransmission and signal termination, (iii) the structure, functi...

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy and Genetics
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Supervisor


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Funder identifier:
https://ror.org/02wdwnk04


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Keywords:
Subjects:
UUID:
uuid:5d0c9f81-2a76-4acf-807f-a2003d362464
Deposit date:
2015-10-12
ARK identifier:

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