Thesis icon

Thesis

Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model

Abstract:

Development of optogenetically controllable human neural network models can provide an investigative system that is relevant to the human brain. Conventional cultures of neural networks in two-dimensions (2D) have major limitations of scale. For instance, the soma of neurons in 2D is unrealistically flattened and both axon and dendrite outgrowth is restricted. Using a combination of tissue engineering techniques and the inclusion of optogenetically modified human induced pluripotent stem c...

Expand abstract

Actions

  • Cite

  • Print

Access Document

Files:

Authors

More by this author
Division:
MSD
Department:
Pharmacology
Department:
Department of Oncology and Institute of Biomedical Engineering
Role:
Author

Contributors

Department:
Department of Oncology
Role:
Supervisor
Department:
Institute of Biomedical Engineering
Role:
Supervisor

Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
UUID:
uuid:5cecda23-6208-4c0f-a800-d5ddccae24d3
Deposit date:
2017-03-25

Terms of use

Views and Downloads





If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP