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Thesis

Collagen-based scaffolds for heart valve tissue engineering

Abstract:

Tissue engineered heart valve (TEHV) is believed to be a promising candidate for curative heart valve replacements. Collagen, elastin and chondroitin-4-sulfate (C4S) comprise the extra-cellular matrix (ECM) of native heart valves and therefore are suitable materials for TEHV scaffolds.

Freeze-drying technique was able to produce scaffolds with relative densities of 0.3%-2.0% and pore sizes of 33.2µm-201.5µm, without having any major effects on the ultra-structures on the scaffold ma...

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Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Research group:
Biomaterials
Oxford college:
Wolfson College
Role:
Author

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Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:5a03aee6-3672-4c29-8d43-64074bbcd467
Local pid:
ora:8995
Deposit date:
2014-09-29

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