Thesis
Gene circuit integration in induced pluripotent stem cells for the study of neurodegeneration
- Abstract:
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The intersection of synthetic biology and human induced Pluripotent Stem cells (iPSC) technology presents a promising avenue for the exploration and treatment of multifactorial disorders. Synthetic biology, through the integration of exogenous gene networks known as gene circuits, enables cellular reprogramming, allowing control over cell behaviour. In parallel, iPSC technology has enabled the development of research models for human cell types that are challenging to obtain, such as neuro...
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- Files:
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(Preview, Dissemination version, pdf, 7.7MB, Terms of use)
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Authors
Contributors
+ Davis, B
- Institution:
- University of Oxford
- Division:
- MSD
- Role:
- Supervisor
+ Buckley, N
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Psychiatry
- Role:
- Supervisor
- ORCID:
- 0000-0003-1152-0653
+ Todd, J
- Institution:
- University of Oxford
- Division:
- MSD
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- Deposit date:
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2025-04-05
- ARK identifier:
Terms of use
- Copyright holder:
- Federico Caso
- Copyright date:
- 2024
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