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The landscape of recombination in African Americans: leveraging human population variation to investigate homologous recombination

Abstract:

Homologous recombination is a highly regulated and complex biological process required for sexual reproduction in humans and many other species. The mechanisms of initiation and control of this process, however, are only partially understood. The aim of this work is to tease apart and utilize the differences in recombination localization between human populations to understand the underlying biological processes.

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Department:
MSD, Clinical Medicine, Wellcome Trust Centre for Human Genetics
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Copyright Holder, Author

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Grant:
RPSD0
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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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