Thesis
The roles of Hsp70 proteins in antigen processing and presentation
- Abstract:
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The ability of members of the hsp70 family to bind to peptides in vivo and in vitro suggests that they may be involved in the processing of antigens for binding to Major Histocompatibility (MHC) class I and/or class n molecules. The aims of this thesis have been to provide evidence for the involvement of hsp70s in antigen processing and to characterise the binding of peptides by hspTOs by structural and functional studies.
Firstly, the peptide-binding domains of t...
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Authors
- Publication date:
- 1997
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Subjects:
- UUID:
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uuid:567dff45-08ce-43b4-b011-d08afea42f76
- Local pid:
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td:602830411
- Source identifiers:
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602830411
- Deposit date:
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2013-01-21
Terms of use
- Copyright holder:
- Winchester, Christopher Charles
- Copyright date:
- 1997
- Notes:
- The digital copy of this thesis has been made available thanks to the generosity of Dr Leonard Polonsky
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