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Algorithms for the correction of photobleaching

Abstract:

The measured intensity (ideally in units of photon counts) of a fluorescent sample over time constitutes a time-series called an intensity trace. The idea of fluorescence fluctuation spectroscopy (FFS) is to extract information from intensity traces.

Photobleaching is the phenomenon of the breaking of fluorophores (light emitters) over time. Photobleaching causes fluorescent signal to diminish over time. This changes the intensity trace, introducing a downward...

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Department:
Hertford College
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Grant:
105278
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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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