Dynamics of RNA transcription and transcript stabilisation in wild-type and mutant Saccharomyces cerevisiae

Thesis

Ribonucleic acids (RNAs) are a diverse and highly dynamic class of molecules. Coding RNAs facilitate the production of proteins from the heritable information stored in deoxyribonucleic acid (DNA), while pervasively transcribed non-coding RNAs have catalytic, scaffolding and regulatory functions.

Since cellular requirements vary with time, cell type and environmental condition, RNA pools are highly dynamic. Steady-state RNA levels are balanced through the production of RNAs via tran...

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Authors: Woloszczuk, R

• DOI: 10.5287/ora-noa9r7age
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English