Thesis
Physiology of neural networks in the dorsal raphe nucleus
- Abstract:
-
5-HT (5-Hydroxy-tryptamine; serotonin) neurons located in the midbrain dorsal raphe nucleus (DRN) are implicated in many brain functions in health including aversive processing and are the target of the first line drug treatment for anxiety and depression, selective serotonin reuptake inhibitors (SSRIs). The research presented in this thesis employs silicon probe electrodes to investigate (1) the diversity of firing properties of both 5-HT and non-5-HT neurons in the DRN, (2) potential eme...
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Authors
Contributors
+ Sharp, T
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pharmacology
- Role:
- Supervisor
- ORCID:
- 0000-0001-7434-9713
+ Holmes, A
- Role:
- Supervisor
+ Bannerman, D
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Psychiatry
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2023-10-23
Terms of use
- Copyright holder:
- O'Sullivan, R
- Copyright date:
- 2023
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