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Journal article

Megavariate genetics: what you find is what you go looking for

Abstract:
The subjectivity or “purpose dependency” of measurement in biology is discussed using examples from high-dimensional medical genetic research. The human observer and study designer tacitly determine the numerical and graphical representation of biological simplicity or complexity via choice of ascertainment (sampling frame), numbers to measure, referential basis, statistical learning formalism and feature search, and also via the selection of display styles (cognitive analogies) for all these quantifications.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1162/biot.2009.4.1.21

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
ORCID:
0000-0002-4558-4981


Publisher:
Springer
Journal:
Biological Theory More from this journal
Volume:
4
Issue:
1
Pages:
21-28
Publication date:
2015-04-14
Acceptance date:
2009-09-29
DOI:
EISSN:
1555-5550
ISSN:
1555-5542


Language:
English
Keywords:
Pubs id:
1266473
Local pid:
pubs:1266473
Deposit date:
2025-11-20
ARK identifier:

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