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Thesis

Dendritic cell maturation, migration and function

Abstract:

Dendritic cells (DC) have a fundamental role in priming naive T-cell responses and a suspected importance in the regulation of central and peripheral tolerance. Before DC can be responsibly used in human clinical trials, the generation of both immature and mature subsets must be standardised and their in vivo migratory and functional characteristics explored.

The generation of human blood monocyte-derived DC in either fetal calf serum (PCS) or autologous plasma (HP) were compared. P...

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Peer review status:
Peer reviewed

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Department:
University of Oxford
Role:
Author
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Source identifiers:
603840456
UUID:
uuid:47d2be37-0508-47d6-8b97-a3cf8e39f9f6
Local pid:
polonsky:2:18
Deposit date:
2017-10-04

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