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Thesis

Physical studies on subunit interactions in oligomeric enzymes

Abstract:

This thesis is concerned with the physical structure and the protein-protein interactions in the two oligomeric proteins, Phosphofructokinase (PFK) and Aldolase. PFK is known to play an important part in the regulation of glycolysis and the activity of the enzyme is modified by a variety of low molecular weight metabolites including ATP, AMP, F-6-P, FDP and citrate. Physical studies on PFK were, therefore, made with particular reference to the conformational changes which might accompany t...

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Institution:
University of Oxford
Oxford college:
Magdalen College
Role:
Author


Publication date:
1970
DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
UUID:
uuid:47664c6b-6be0-444f-b49a-2ab1584a7635
Local pid:
td:601870657
Source identifiers:
601870657
Deposit date:
2015-03-26
ARK identifier:

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