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Thesis

The role of lung tissue-resident memory T cells in protection against tuberculosis

Abstract:

Tuberculosis (TB) is a global health problem, which is proving extremely difficult to control in the absence of an effective vaccine. Bacille Calmette-Guérin (BCG), the only vaccine currently licensed against TB, demonstrates variable efficacy in humans and cattle. A greater understanding of what constitutes a protective host immune response is required in order to aid the development of improved vaccines. Tissue-resident memory T cells (TRM) are a recently-identified subset of...

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Naomi Bull More by this author

Contributors

Department:
The Jenner Institute
Role:
Supervisor
Department:
Animal and Plant Health Agency
Role:
Supervisor
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Funding agency for:
Helen McShane
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Grant:
SE3266
Funding agency for:
Philip Hogarth
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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