Thesis
Metabolomic profiles and prostate cancer risk
- Abstract:
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Pre-diagnostic blood metabolites may help identify novel risk factors for prostate cancer incidence, and these metabolite profiles may be modifiable through lifestyle and dietary factors. For this thesis, I investigated circulating metabolites in relation to (a) potential determinants and (b) prostate cancer risk, using EPIC and the UK Biobank for two of the largest prospective studies to date of metabolites and prostate cancer risk.
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In EPIC, plasma metabolites were measured by liquid...
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(Preview, Dissemination version, pdf, 9.2MB, Terms of use)
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Authors
Contributors
+ Wrightson, R
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Nuffield Department of Population Health
- Sub department:
- Cancer Epidemiology Unit
- Oxford college:
- Wolfson College
- Role:
- Supervisor
- ORCID:
- https://orcid.org/0000-0002-9571-0763
+ Smith Byrne, K
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Nuffield Department of Population Health
- Sub department:
- Cancer Epidemiology Unit
- Role:
- Supervisor
- ORCID:
- https://orcid.org/0000-0002-1932-7463
+ Schmidt, J
- Institution:
- Aarhus University
- Research group:
- Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus, University Hospital, Aarhus, Denmark
- Role:
- Supervisor
- ORCID:
- orcid.org/0000-0002-7733-8750
+ Allen, N
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Nuffield Department of Population Health
- Sub department:
- Clinical Trial Service Unit
- Role:
- Examiner
- ORCID:
- https://orcid.org/0000-0003-1938-5038
+ Lane, A
- Institution:
- University of Bristol
- Research group:
- Bristol Population Health Science Institute, Cancer, Bristol Medical School (PHS)
- Role:
- Examiner
- ORCID:
- https://orcid.org/0000-0002-7578-4925
+ Cancer Research UK
More from this funder
- Funder identifier:
- https://ror.org/054225q67
- Funding agency for:
- Grenville, Z
- Grant:
- C8221/A30904
- Programme:
- Cancer Research UK Scholarship Package for the University of Oxford
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- Deposit date:
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2026-05-12
- ARK identifier:
Terms of use
- Copyright holder:
- Zoe Grenville
- Copyright date:
- 2025
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