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Thesis

Microstructure imaging with diffusion MRI and microscopy

Abstract:

Diffusion MRI is a powerful, non-invasive tool for microstructure imaging because of its sensitivity to structures on the microscopic scale. By analysing the diffusion signal we can infer the structural connectivity of the human brain or changes in the myelo- and cyto-architecture. This inference requires biophysical signal modelling, where we aim to map macroscopic diffusion signals onto biologically-meaningful tissue parameters. However, this mapping is often ill-posed, with multiple par...

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Division:
MSD
Department:
Biomedical Services
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Miller, K
Howard, A
Jbabdi, S
Grant:
WT203139/Z/16/Z
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Funding agency for:
Miller, K
Grant:
WT202788/Z/16/A
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Funding agency for:
Howard, A
Grant:
MR/L009013/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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