Thesis
Tetramates as antibacterial and anticancer core scaffolds
- Abstract:
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This thesis is concerned with the synthesis of small molecules that mimic tetramate- and pyrrolidinone-containing natural products, and the evaluation of their antibacterial and anticancer properties.
Chapter 1 exposes the need for new antibiotics due to the emergence of resistance to current drugs, and it discusses the value of the natural product inspired approach for drug discovery. It also gives an overview of the structure, synthesis and biological properties of the natural...
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Keywords:
Terms of use
- Copyright date:
- 2016
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