- Abstract:
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The epicardium, a cell layer enveloping the heart muscle, drives embryonic heart development and heart repair in the adult zebrafish. Previous studies found the epicardium to consist of multiple cell populations with distinct phenotypes and functions. Here, I investigated epicardial heterogeneity in the developing zebrafish heart, focusing on the developmental gene program that is also reactivated during adult heart regeneration. Transcription factor 21 (Tcf21), T-box 18 (Tbx18) and Wilms’...
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- Department:
- DPAG Oxford
- Role:
- Supervisor
- Department:
- DPAG Oxford
- Role:
- Supervisor
- Department:
- WIMM Oxford
- Role:
- Supervisor
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Keywords:
- Subjects:
- Copyright date:
- 2017
Thesis
Epicardial heterogeneity during zebrafish heart development
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Authors
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+ Filipa Simoes
+ Paul Riley
+ Roger Patient
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