Journal article : Review
Recent progress in the total synthesis of pyrrole-containing natural products (2011-2020)
- Abstract:
- Natural products have long served as a rich resource for drug discovery in the treatment of illnesses and chronic diseases. Among many families exhibiting fascinating structural complexity and impressive bioactivity, pyrrole-containing natural products frequently present a significant challenge to practitioners of organic synthesis. As a result, synthetic chemists have paid intense attention to the construction of such frameworks, not least as the amounts of natural product isolated from their natural source is often far less than that needed for biological testing. This review discusses total syntheses of pyrrole-containing natural products over the last ten years, highlighting recent advances in the chemistry of pyrroles both in the context of their innate reactivity, and their preparation in complex settings.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Accepted manuscript, pdf, 7.1MB, Terms of use)
-
- Publisher copy:
- 10.1039/d0qo01574a
Authors
- Publisher:
- Royal Society of Chemistry
- Journal:
- Organic Chemistry Frontiers More from this journal
- Volume:
- 8
- Issue:
- 19
- Pages:
- 5550-5573
- Publication date:
- 2021-07-29
- Acceptance date:
- 2021-07-27
- DOI:
- EISSN:
-
2052-4129
- ISSN:
-
2052-4129
- Language:
-
English
- Keywords:
- Subtype:
-
Review
- Pubs id:
-
1186306
- Local pid:
-
pubs:1186306
- Deposit date:
-
2021-11-23
- ARK identifier:
Terms of use
- Copyright holder:
- Partner Organisations
- Copyright date:
- 2021
- Rights statement:
- © the Partner Organisations 2021
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Royal Society of Chemistry at: https://doi.org/10.1039/D0QO01574A
If you are the owner of this record, you can report an update to it here: Report update to this record