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Thesis

Lipid-protein interactions and nicotinic acetylcholine receptor function

Abstract:

The effect of bilayer composition, specifically the presence of cholesterol, upon the function of the reconstituted nicotinic acetylcholine receptor (nAcChoR) was investigated using stopped-flow fluorescence. The nAcChoR was purified and reconstituted from the electroplaques of Torpedo nobiliana, using affinity column chromatography, into bilayers of defined composition and the function of each sample assessed and compared with tho...

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Peer review status:
Peer Reviewed

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Department:
University of Oxford
Role:
Author
This thesis was digitised thanks to the generosity of Dr Leonard Polonsky More from this funder
Publication date:
1996
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Local pid:
polonsky:4:13

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