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Thesis

Understanding and modulating vessel formation in human rotator cuff tendon disease

Abstract:

Tears of the rotator cuff tendons are common and often debilitating causing pain and loss of upper limb function. Their prevalence continues to increase as populations age. Although the pathobiology of tendon disease is incompletely understood, it is increasingly evident that inflammation plays a critical role. Persistent immune cell infiltration, fibroblast activation and angiogenesis are cardinal features of rotator cuff tendon disease.

Unfortunately, the surgical repair of rot...

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Division:
MSD
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Supervisor
ORCID:
0000-0002-7052-3793
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Supervisor
ORCID:
0000-0001-5940-1464
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Examiner
ORCID:
0000-0001-6924-6402
Institution:
ETH Zurich
Role:
Examiner

More from this funder
Funder identifier:
http://dx.doi.org/10.13039/501100000297
Programme:
Royal College of Surgeons/ Dunhill Foundation Joint fellowship

DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Language:
English
Keywords:
Subjects:
Pubs id:
1670020
Local pid:
pubs:1670020
Deposit date:
2021-09-15
ARK identifier:

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