Thesis
Dynamic nuclear polarisation as a probe of metabolism in pathophysiology
- Abstract:
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Spin-half nuclei in a magnetic field possessing a population difference in excess of that expected at thermal equilibrium are said to be hyperpolarised. Dynamic Nuclear Polarisation (DNP) is a method to generate hyperpolarised systems, pumping nuclear spins into a given state at low temperature. Hyperpolarised samples can be rapidly dissolved in a hot solvent, and maintain a highly polarised spin population that relaxes to the new thermal equilibrium over several minutes. It is possible to...
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- Files:
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(Preview, pdf, 284.3MB, Terms of use)
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Authors
Contributors
+ Tyler, D
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Physiology Anatomy & Genetics
- Role:
- Supervisor
+ Sibson, N
- Department:
- Oncology
- Role:
- Supervisor
+ Jones, H
- Department:
- Physics
- Role:
- Supervisor
+ Tucker, S
- Department:
- Physics
- Role:
- Supervisor
+ Gadian, D
- Department:
- University College London
- Role:
- Examiner
+ British Heart Foundation
More from this funder
- Grant:
- FS/10/002/28078, FS/14/17/30634, FS/11/50/29038, & RG/11/9/28921
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- UUID:
-
uuid:3d6721e0-e57c-42af-91a8-4d2f6d68da5b
- Deposit date:
-
2016-03-30
- ARK identifier:
Terms of use
- Copyright holder:
- Miller, J
- Copyright date:
- 2015
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