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Thesis

Developmental response to brain inflammation

Abstract:

Perinatal inflammation contributes to neurodevelopmental diseases, and animal models have revealed that the inflammatory response within the central nervous system is age dependent. It remains unclear what intrinsic and/or extrinsic factors are responsible for this variation. Here, my aim was to discover the mechanisms responsible for the age-dependent changes in the inflammatory response of the brain by injecting interleukin-1 (IL-1β) into the brain of mice at postnatal day (P)7, P14, P21...

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Department:
Department of Pharmacology and Somerville College, University of Oxford, UK
Role:
Supervisor
Department:
Department of Perinatal Imaging & Health, King's College London, UK
Role:
Supervisor
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Grant:
SFRH/BD/51703/2011
Funding agency for:
Inês Tavares Pinto de Sá Pereira
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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