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Thesis

Metabolomic characterisation of acidosis in severe falciparum malaria

Abstract:

Severe falciparum malaria is a potentially lethal parasitic infection for which the treatment remains suboptimal as the pathophysiology is incompletely understood. Acidosis is the strongest predictor of death, caused by an accumulation of acids of which some are known, such as L-lactate, while others remain unidentified. The aim of this thesis was to further characterise metabolic acidosis in severe falciparum malaria by establishing the identity and source of the unidentified non-lactate...

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MSD
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Author

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Funding agency for:
Leopold, S
Wellcome Trust More from this funder
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Funding agency for:
Leopold, S
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
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UUID:
uuid:3a089f85-39dc-478f-b627-37accb5004ea
Deposit date:
2019-03-27

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