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Thesis

Elucidating the non-apoptotic role of the caspases in the Drosophila intestinal system

Abstract:

The deregulation of caspase activity and stem cell properties are often correlated with the appearance and propagation of cancer, including colorectal cancer. However, the caspase-dependent regulation of the intestinal system remains poorly understood. Taking advantage of the powerful genetic tractability of Drosophila melanogaster, I aimed to decipher the functional role of the caspases within the intestinal system, in addition to their role in tumour formation. In this thesis, I...

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Division:
MSD
Department:
Pathology Dunn School
Role:
Author

Contributors

Role:
Supervisor
Role:
Examiner
Department:
Oxford Brookes
Role:
Examiner
Edward Penley Abraham Research Fund More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:397ebd2d-e77a-4d76-8a35-2112d94bb4dd
Deposit date:
2019-12-17

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