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Thesis

Characterisation of a cluster of novel genes in the human major histocompatibility complex

Abstract:

The human MHC has been shown to be associated with susceptibility to a large number of diseases. Within the MHC class III region, which consists of a ~1,100kb segment of DNA located between the class I and class II multigene families, at least 38 genes have been identified, some of which could be involved in disease susceptibility. Analyses of the homologous mouse H-2S region have localised two loci responsible for susceptibility to experimental autoimmune orchitis, Orch-1

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Peer review status:
Peer reviewed

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Department:
University of Oxford
Role:
Author


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


UUID:
uuid:3340fd57-26ca-4172-8f85-0fb07f2d7d24
Local pid:
polonsky:2:38
Source identifiers:
603828033
Deposit date:
2017-10-04

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