Thesis
Mechanisms of serotonergic control in fear-related neural circuits and behaviour
- Abstract:
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Serotonin (5-HT) neurotransmission is strongly implicated in affective psychopathologies, with first-line drugs selectively targeting the 5-HT system. Further evidence for the role of 5-HT as an important regulator of emotional states comes from human gene association studies. These have identified polymorphic variants of the 5-HT transporter (5-HTT) gene with reduced transcription efficacy. Lower 5-HTT expression associates with susceptibility to affective disorders and heightened amygdal...
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- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
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uuid:333590cf-964d-44dd-8f5b-4d492e15f8b2
- Deposit date:
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2018-02-23
Terms of use
- Copyright holder:
- Sengupta, A
- Copyright date:
- 2017
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