Multi-scale effects of stretch on peripheral nerves

Thesis

Peripheral nerve injury, leading to loss of motor and sensory function, is a burdensome consequence of trauma, surgery or chronic conditions. Mechanical forces play a substantial role in the onset of injury, and affect peripheral nerves at varying length scales, from tissues to individual cells. A multi-scale approach is therefore required to understand how supraphysiological levels of deformation at the nerve level can affect function at the single-cell level.

The aim of this proj...

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Authors: Bianchi, F

• DOI: 10.5287/ora-00a9zkjn7
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Subjects: Biomechanics; Stem Cels; Nerve mechanics; Nerve damage; Tissue Engineering