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Thesis

The biosynthesis of β-lactams

Abstract:

This thesis reports the work done on two research projects which were carried out independently of each other but converge on the central theme of β-lactam biosynthesis. Chapter 1 provides an overview of biosynthesis in secondary metabolism, with special emphasis on current knowledge about the β-lactams.

The first project, covered from Chapters 2 to 5, was part of our group's continuing effort to understand the structure and mechanism of Ring Expandase-Hydroxylase (REXH), an enzyme...

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Institution:
University of Oxford
Department:
Mathematical and Physical Sciences Division

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Role:
Supervisor
Publication date:
1993
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
602836999
URN:
uuid:24b6b29d-87cc-48f2-bd1b-bb64c663604f
Local pid:
td:602836999
Language:
English
Subjects:

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