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Thesis

Studies of interactions of staphylococcal and streptococcal peptides with a type-I module pair of human fibronectin

Abstract:

A number of pathogenic bacteria, such as Staphylococcus aureus and Streptococcus pyogenes, can adhere to the protein fibronectin (Fn) in the human extracellular matrix. These host/pathogen interactions are likely to play an important role in the process of infection and have therefore been identified as targets for new therapeutics. Numerous proteins from grampositive bacteria have been shown to bind to the N-terminal part of Fn, which contains five F1 modules (1-5

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Peer review status:
Peer Reviewed

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Department:
University of Oxford
This thesis was digitised thanks to the generosity of Dr Leonard Polonsky More from this funder
Publication date:
2002
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Local pid:
polonsky:1:23

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