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Thesis

LD-based SNP and genotype calling from next-generation sequencing reads.

Abstract:

Next-generation sequencing is revolutionising in genetics, where base-by base information for the whole genome is available for a large sample of individuals. This type of data is becoming commonly used and will continue to be in the near future. One of the first questions arising is the identification of novel variants and subsequently genotype calling of the individuals in the sample. However, given the cost of sequencing, so far most projects are sequencing individuals in low to medium ...

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Institution:
University of Oxford
Research group:
Mathematical Genetics
Oxford college:
St Anne's College
Department:
Mathematical,Physical & Life Sciences Division - Statistics

Contributors

Role:
Supervisor
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:2093d498-3e7f-4648-9fde-fcdb311849de
Local pid:
ora:9374

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