Thesis
Large-scale layered systems and synthetic biology: model reduction and decomposition
- Abstract:
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This thesis is concerned with large-scale systems of Ordinary Differential Equations that model Biomolecular Reaction Networks (BRNs) in Systems and Synthetic Biology. It addresses the strategies of model reduction and decomposition used to overcome the challenges posed by the high dimension and stiffness typical of these models. A number of developments of these strategies are identified, and their implementation on various BRN models is demonstrated.
The goal of model reduction is...
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Funding
+ Engineering and Physical Sciences Research Council
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Funding agency for:
Thomas Paul Prescott
Bibliographic Details
- Publication date:
- 2014
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- URN:
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uuid:205a18fb-b21f-4148-ba7d-3238f4b1f25b
- Local pid:
- ora:11689
Item Description
- Language:
- English
- Keywords:
- Subjects:
Terms of use
- Copyright holder:
- Thomas P Prescott
- Copyright date:
- 2014
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