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Phagocytosis of antigens by Langerhans cells

Abstract:

Mature dendritic cells (DC) isolated from lymphoid tissues initiate antigen-specific T-dependent responses even though they are non-phagocytic and weakly pinocytic, whereas Langerhans cells (LC; immature DC) can process protein antigens but are poorly immunostimulatory. Thus antigens may be acquired by cells of this lineage at an immature stage but, to our knowledge, there have been no studies on the phagocytic capacity of these cells in vitro.

Using a newly-developed flow...

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Institution:
University of Oxford
Division:
MSD
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
1992
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:1f69e0f0-1d08-4c2f-aa02-216231100f14
Local pid:
td:603851241
Source identifiers:
603851241
Deposit date:
2013-10-21

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