Thesis icon

Thesis

Investigation of ʟ-amino acid hydroxylases

Abstract:

Ferrous-iron/2-oxoglutarate(2-OG)-dependent oxygenases have emerged as a widely distributed family of oxygenases. They have applications both in biocatalysis and as pharmaceutical/agrochemical targets. One of the first subfamilies of 2-OG oxygenases to be studied in detail were the prolyl hydroxylases. The work described in my thesis focused on substrate analogue studies on the proline hydroxylases and on a highly unusual type of 2-OG oxygenase that catalyses the production of ethylene fro...

Expand abstract

Actions


Authors


Contributors

Department:
Organic Chemistry
Role:
Supervisor
Type of award:
DPhil
Awarding institution:
University of Oxford

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP