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Thesis

Harnessing the immune system to reject cancers through genetic modifications of tumour cells

Abstract:

The immune system, which defends the body against a wide array of threats, is gaining a growing role in the fight against cancer. For an immunotherapy to be successful, it needs to overcome intrinsically weak tumour-specific immune responses. There are two broad approaches to achieving this goal: targeting the various arms of the immune system or targeting the cancer and its microenvironment. The experiments discussed in this thesis adopt the second approach. Tumours were transduced with a...

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author

Contributors

Division:
MSD
Department:
Oncology
Role:
Supervisor
Division:
MSD
Department:
Oncology
Role:
Supervisor
Oxford Cancer Imaging Centre More from this funder
Cancer Research UK More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:1aafa1f4-ee10-4081-b621-d81b9979d96a
Deposit date:
2015-10-28

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