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Thesis

Sleep, circadian and behavioural characterisation of two schizophrenia-relevant transgenic mouse models

Abstract:

The experiments described in this thesis involved the sleep, circadian and behavioural characterisation of two schizophrenia-relevant transgenic mouse models, both of which are models of altered glutamatergic function. Although schizophrenia cannot be recapitulated in rodents, the study of transgenic mouse models can yield insights into the roles of schizophrenia candidate genes in brain function and dysfunction.

D-amino acid oxidase knockout (Dao-/-) mi...

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Institution:
University of Oxford
Research group:
Peirson Group
Oxford college:
Wadham College
Department:
Medical Sciences Division - Ophthalmology

Contributors

Role:
Supervisor
Publication date:
2015
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:1853944f-8ee1-4ed8-9214-d8a61c6bb46d
Local pid:
ora:12368

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