Thesis
Sterol metabolism in extra-hepatic tissues
- Abstract:
-
It is currently believed that cholesterol is the principal precursor of steroid hormones in endocrine organs and that it is converted to hormones via pregnenolone. The cholesterol molecule is first hydroxylated at C-20, and then at C-22 to yield 20α,22ζ-dihydroxy-cholesterol and this is then cleaved between C-20 and C-22 to yield pregnenolone and isocaproic acid./p>
The enzyme system catalysing this series of reactions (cholesterol oxidase, E.C. 1.1.3.6) has been investigated in some...
Expand abstract
Actions
Access Document
- Files:
-
-
(Preview, pdf, 2.5MB, Terms of use)
-
Authors
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
-
uuid:1754a728-9db1-43cb-b82c-820258e8d150
- Local pid:
-
polonsky:15:9
- Source identifiers:
-
601870804
- Deposit date:
-
2017-10-05
- ARK identifier:
Terms of use
- Copyright holder:
- Raggatt, P; Raggatt, Peter Rufus
- Copyright date:
- 1967
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
If you are the owner of this record, you can report an update to it here: Report update to this record