Thesis
The psychiatric and neural effects of L-type calcium channel antagonism: pharmacoepidemiology and experimental medicine studies
- Abstract:
-
L-type calcium channel (LTCC) antagonists are used to manage cardiovascular conditions. However, several factors suggest they may also have therapeutic potential in psychiatry. First, there is evidence for calcium signalling abnormalities in bipolar disorder (BD). Second, there is some evidence, albeit very inconclusive, that LTCC antagonists may have beneficial effects in BD. Third, calcium channel genes are involved in a number of psychiatric conditions. In particular, genome-wide associ...
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Authors
Contributors
+ Harrison, P
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Psychiatry
- Role:
- Supervisor
+ Capitão, L
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Psychiatry
- Role:
- Supervisor
+ Geddes, J
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Psychiatry
- Role:
- Supervisor
+ Wellcome Trust
More from this funder
- Funder identifier:
- https://ror.org/029chgv08
- Grant:
- 211024/Z/18/Z
- Programme:
- Doctoral Training Fellowship for Clinicians
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2024-08-06
Terms of use
- Copyright holder:
- Colbourne, CL
- Copyright date:
- 2024
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