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The structure of alphoid satellite DNA on normal and abnormal human Y chromosomes

Abstract:

The long-range structure of the Y chromosome alphoid satellite DNA has been determined in the cell lines 3E7 and OXEN. Variation in alphoid DNA block size and restriction enzyme sites were observed. The alphoid block size and restriction enzyme site variations were determined for a collection of 42 normal Y chromosomes. The alphoid DNA polymorphisms observed denned 24 Y chromosome alleles. Unexpectedly, the Y alphoid DNA alleles analysed revealed two distinct groups of Y chromosomes indic...

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Institution:
University of Oxford
Department:
Life and Environmental Sciences Division

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Role:
Supervisor
Role:
Supervisor
Publication date:
1989
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603835883
URN:
uuid:162cb1a7-3176-4b56-be8b-353b65fee236
Local pid:
td:603835883
Language:
English
Subjects:

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