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Thesis

Neuropharmacological studies of antidepressant action on brain dopamine systems

Abstract:

There is compelling evidence to suggest that several core symptoms of severe depressive illness (anhedonia, loss of motivation and psychomotor retardation) arise as a consequence of abnormal neurotransmission within the mesocorticolimbic system. Moreover, changes in transmitter function within this circuitry are thought to contribute to the therapeutic effect of antidepressant treatments. A key output station of the mesocorticolimbic ...

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Institution:
University of Oxford
Department:
Faculty of Clinical Medicine
Publication date:
1998
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603850381
URN:
uuid:15c300a8-1395-4a8c-be8e-474c42c5a5b5
Local pid:
td:603850381

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