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Thesis

Endothelial activation in experimental metastasis models

Abstract:

The majority of cancer related deaths occur due to the invasive growth of metastatic lesions. In the early stages of metastasis, circulating cell interact with the endothelial cells to establish at a distant site. In inflammation endothelial activation results in induction of adhesion molecules on the endothelium that participate in the homing of leukocytes. Because of the interactions of metastatic cells with the endothelium, the question was whether some of the characteristic molecules o...

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Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Oxford college:
Brasenose College
Department:
Medical Sciences Division - Radiation,Oncology and Biology
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:14ecdd1d-0acb-458a-b11e-6543779b2a2f
Local pid:
ora:10189

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