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Thesis

Genetic and genomic analysis of Arabidopsis thaliana with low-coverage next-generation sequencing data

Abstract:

Next-generation sequencing technologies have transformed our understanding of genetic variation segregating in populations and its relationship with phenotypic traits. Sequencing large populations at low coverage, thus sampling only a fraction of the genome of each individual, may increase statistical power in genetic mapping [Pasaniuc,2012] compared to genotyping arrays. This thesis explores several novel applications of low-coverage population-based sequencing, using data from 488 recomb...

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Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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