Thesis
Widening the therapeutic window of thoracic radiotherapy: cardiopulmonary toxicity modelling
- Abstract:
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Introduction: Prognosis for locally advanced non-small cell lung cancer (LANSCLC) remain poor despite attempts with radiation dose escalation to improve overall survival (OS). A major limitation of radiation dose escalation is normal tissue toxicity. Here, I investigate the hypothesis that cardiac and its substructure irradiation impact OS in LA-NSCLC patients with a dose-volume-time effect. As cardiac avoidance can potentially increase lung toxicity (radiation pneumonitis (RP)...
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Funding
Cancer Research UK
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
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uuid:133facbb-ed8c-41aa-b1f0-eccadfd8cc0b
- Deposit date:
- 2019-05-03
Related Items
Terms of use
- Copyright holder:
- Vivekanandan, S
- Copyright date:
- 2019
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