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Thesis

Quantitative T2 imaging of whole post-mortem brains in ALS

Abstract:

Quantitative MRI has promise to provide precise measures for assessing neurological disorders such as amyotrophic lateral sclerosis (ALS). While MRI is very sensitive to pathological changes in tissue, it lacks the specificity needed for biological interpretability. One way to address this is to compare MRI to more direct measurements, such as histopathology. In this thesis, I present methods that enable direct comparison of quantitative T2 imaging to histopathology in the same post-mortem...

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Division:
MSD
Department:
Clinical Neurosciences
Department:
FMRIB, Oxford University
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:12a1a621-3b68-4489-a2db-c3f83575e8e7
Deposit date:
2019-08-05

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