Thesis
Structural biochemistry of the Tol-Pal inner membrane protein assembly
- Abstract:
-
Understanding fundamental processes within bacteria is crucial to building new approaches to tackle the problem of antimicrobial resistance. In particular, the cell envelope is a key focus as it is a target for current and future antibiotics. The Gram-negative cell envelope typically comprises of an outer membrane (OM), cell wall and inner membrane (IM). The OM acts as a barrier to the outside world and can confer intrinsic resistance to antibiotics. However, the OM is non-energised and so...
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Authors
Contributors
+ Kleanthous, K
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Biochemistry
- Role:
- Supervisor
- ORCID:
- 0000-0002-3273-0302
+ Newstead, S
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Biochemistry
- Role:
- Supervisor
+ Wellcome Trust
More from this funder
- Funder identifier:
- http://dx.doi.org/10.13039/100010269
- Funding agency for:
- Press, C
- Grant:
- 220066/Z/20/Z
- Programme:
- DPhil Structural Biology
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2023-04-03
Terms of use
- Copyright holder:
- Press, C
- Copyright date:
- 2022
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