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Thesis

Applications of whole genome sequencing to understanding the mechanisms, evolution and transmission of antibiotic resistance in Escherichia coli and Klebsiella pneumonia

Abstract:

Whole genome sequencing (WGS) has transformed molecular infectious diseases epidemiology in the last five years, and represents a high resolution means by which to catalogue the genetic content and variation in bacterial pathogens.

This thesis utilises WGS to enhance our understanding of antimicrobial resistance in two clinically important members of the Enterobacteriaceae family of bacteria, namely Escherichia coli and Klebsiella pneumoniae. These organis...

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Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Oxford college:
Brasenose College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
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Funding agency for:
Nicole Elinor Stoesser
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:10ed1097-b2a1-4e3e-a4b3-58318d325f89
Local pid:
ora:10643

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