Journal article
Vascular phenotype identification and anti-angiogenic treatment recommendation: a pseudo-multiscale mathematical model of angiogenesis
- Abstract:
-
The development of anti-angiogenic drugs for cancer therapy has yielded some promising candidates, but novel approaches for interventions to angiogenesis have led to disappointing results. In addition, there is a shortage of biomarkers that are predictive of response to anti-angiogenic treatments. Consequently, the complex biochemical and physiological basis for tumour angiogenesis remains incompletely understood. We have adopted a mathematical approach to address these issues, formulating a ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1016/j.jtbi.2016.03.002
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Authors
Funding
+ Systems Approaches to Biomedical Sciences Centre for Doctoral Training
More from this funder
Funding agency for:
Hutchinson, L
Grant:
EP/G037280/1
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Hutchinson, L
Grant:
EP/G037280/1
+ F. Hoffman La-Roche Ltd
More from this funder
Funding agency for:
Hutchinson, L
Grant:
EP/G037280/1
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Theoretical Biology Journal website
- Volume:
- 398
- Pages:
- 162–180
- Publication date:
- 2016-01-01
- Acceptance date:
- 2016-03-03
- DOI:
- EISSN:
-
1095-8541
- ISSN:
-
0022-5193
- Source identifiers:
-
611895
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:611895
- UUID:
-
uuid:0fa35a82-1121-47e2-a586-ae27b9faf1aa
- Local pid:
- pubs:611895
- Deposit date:
- 2016-04-07
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 Elsevier Ltd.
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