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Thesis

Impact of genetic variation on gene regulatory effects of vitamin D in immunity and inflammation

Abstract:

Genome-wide association studies in multifactorial diseases have contributed to our understanding of genetic risk and defined specific disease-associated loci in particular populations. However, risk cannot be fully explained by genetics and evidence points to both genetic and environmental factors being important in causation and pathophysiology. The role of vitamin D in calcium homeostasis is well established. Over the last 30 years it has become clear that vitamin D has a wider role in phys...

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Institution:
University of Oxford
Research group:
Julian Knight Group
Oxford college:
Wolfson College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Wellcome Trust Centre for Human Genetics
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:0f4679e7-7ef6-49e6-ab04-5fc280f1d680
Local pid:
ora:11821

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